Monospot: a differential slide test for infectious mononucleosis.
نویسندگان
چکیده
Sera collected from 372 patients with suspected infectious mononucleosis were examined for heterophile antibodies by the Paul-Bunnell and the Monospot test. Comparison of results showed the latter to be simple, time saving, and of sufficient specificity for routine use in the general laboratory.
منابع مشابه
Monospot : a differential slide test for infectious mononucleosis VIVIAN BASSON AND
For many years, the Paul-Bunnell reaction (Paul and Bunnell, 1932) to demonstrate the presence of heterophile antibodies to sheep red cells has been accepted as a specific test for establishing the diagnosis of infectious mononucleosis. Stuart (1935), Bailey and Raffel (1935), and Davidsohn and Walker (1935) independently differentiated the antibodies for Forssman antigen and those of serum sic...
متن کاملA comparison of the Monospot with the Paul-Bunnell test in infectious mononucleosis and other diseases.
The Monospot is a spot test designed for the diagnosis of infectious mononucleosis and its efficacy has been compared with that of the standard Paul-Bunnell test. Three out of 210 (1.4%) sera from normal persons and persons suffering from diseases other than infectious mononucleosis gave ;false' positive results when compared with the Paul-Bunnell test. Using 38 sera from patients with strong c...
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A slide test for infectious mononucleosis using formalinized horse erythrocytes (Monotest(2)) was quantitated and compared with standard differential heterophile (Davidsohn) titres performed on the same specimens. The Monotest titre parallels the standard presumptive heterophile (antisheep cell) titre in the degree of elevation, with a ratio of Monotest to heterophile titre of approximately 1 t...
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The diagnosis of an acute episode of infectious mononucleosis (IM) is made on the basis of clinical symptoms and serological evidence for development of heterophile antibodies. In an effort to obtain a very sensitive and specific assay for diagnosis of IM, we have developed MERISTAR:IM. The MERISTAR assay uses latex beads coated with purified bovine heterophile antigen. We compared the sensitiv...
متن کاملIn reference to "use of the lymphocyte count as a diagnostic screen in adults with suspected Epstein-Barr virus infectious mononucleosis".
We read the recent article by Biggs et al. on the use of the absolute lymphocyte count in the diagnosis of infectious mononucleosis. We carried out a similar study on the use of the lymphocyte to white cell ratio, and later reanalyzed our data using an absolute lymphocyte count above 4, in response to an earlier study carried out by Biggs et al. We would like to highlight the divergence in resu...
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عنوان ژورنال:
- Journal of clinical pathology
دوره 22 3 شماره
صفحات -
تاریخ انتشار 1969